【人物介绍】惠永正，男，1939年12月生，江苏苏州人。1962年毕业于北京大学化学系；1962年9月，中科院上海有机化学研究所从事研究工作曾任副所长、所长；1990-1998.03国家科委副主任，1998.04-2000.03科技部副部长。2000年3月退休。
1959.9－1962.7北京大学
1962.9－ 中科院上海有机化学研究所
1982.2－1983.1 美国 University of North Carolina at Chapel Hill
1983.2－1983 12 美国 Rutgers University
1991.1－ 国家科委[1]
【主要工作成就】惠永正早期从事物理有机化学研究，系统地研究了糖淀粉极其衍生物作为宿主体系的宿主－客体化学， 随后研究领域扩展到计算机化学和微泡体化学。近年来主要从事微泡体化学和糖化学研究，包括长链、多氟代长链化物的微泡体的性质和生物合功能模拟: 复杂寡糖的化学合成及糖缀合物中糖链与生物功能之间关系的研究。早年曾从事计算机化学和微环境效应研究，曾获全国科学大会奖(1978)，中科院科学进步一等奖(1986)，国家自然科学三等奖(1988)，和中科院发明一等奖(1997)。至今共发表论文71篇。共培养硕士研究生7，博士研究生6名，合作培养博士生8名[2]。
【现从事的研究领域】糖化学
【近年发表论文目录】1. Inter-Domain Movenment of Spin Lables in the Vesicle Monolayers of Hybride bolaamphiphiles.
B.Yu, Y.Z.Hui,Supramolecular Chem.,1995,5, 193-195
2. Direct Facile Tetrahydrofuranylation of Alcohols in p-TsCl/NaH/THF System.
B.Yu, Y.Z.Hui,Synth. Commun.,1995,25, 2037
3. A New Highly Regioselective Reaction of Unprotected Sugars for Chemical Synthesis of -Acyl-D-glucopyranosides.
J.Xia, Y.Z.Hui,Synth. Commun.,1995,25, 2235-2251
4. An Efficient and Stereospecific Synthesis of 1-Stearoyl-2-[(z,z,z)-9,12,15-Linolenoyl]-sn-Glycerophosphocholine and its Bioactivity.
J.Xia, Y.Z.Hui,Bioorg. Med. Chem. Lett.,1995,5(17),1919-1922
5. A New Strategy for the Stereoselective Synthesis of 2,3-Dideoxy-3-Fluoro-D-Ribofuranose Derivatives.
Z.W.Guo, B.G.Huang, W.J.Xia, Y.Z.Hui, S..Lang,Chin. J. Chem.,1995,13,363
6. Chemical Synthesis of a Commonly Occurring Saponin Trisaccharide: a -L-Rhaminosyl-(1-4)-b nosyl-(1-6)-D-Glucopyranose.
M.Z.Liu, Z.W.Guo, Y.Z.Hui,Carbonhydr. Lett.,1995,1, 387-392
7. An Efficient and Stereospecific Synthesis of 1-Palmitoyl-2-[(z,z,z)-9,12,15-Linolenoyl]-sn-Glycerophophocholine.
J.Xia, Y.Z.Hui,Chin. Chem. Lett.,1995,6(10),863-866
8. A General Method for the Synthese of Ether Phospholipids with a -Linolenic Acid and Their Properties.
J.Xia, Y.Z.Hui,Bioorg. Med. Chem. Lett.,1995,5(23),2815-2820
9. A New Highly Regioselective Reaction of Unprotected Sugars for Chemical Synthesis of Methyl-6-D-Acyl-D-Glycopyranoside by Means of Chlorophosphoric Acid Diethyl Ester as Condensing Reagent.
J.Xia, Y.Z.Hui,Synth. Commun,1996,26(2),269-278
10. A Convenient Method for Highly Selective Deprotection of Benzylidene Acetals from Sugars
J.Xia, Y.Hui,Synth. Commum.,1996,26(5),881-886
11. The TMSOTf-Promoted "One Pot" -Glycosidations of Peracetylated Chitobiose.
B.Yu, Q. Ouyang, C.Li, Y.Z.Hui,J. Carbohydr. Chem.,1996,15(3),297-302
12. Chemical Synthesis of (3-SO3Na) GlcNAc b 1-3Fuc b 1-OMe: The Oligocaccharide Involved in the Cell Aggregation of the SpongeMicrocina Prolifera.
Z.W.Guo, S.J.Deng, Y.Z.Hui,J. Carbohydr. Chem.,1996,15(8),965-974
13. A New Strategy for the Stereoselective Syntheses of C-Glycosyl Compounds of b -Pentapyranoses.
Z.W.Guo, Y.Z.Hui,Synth. Commun.,1996,26(11),2067-2073
14. Supramolecular Assemblies from Single-Chain Hydrocarbon Fluorocarbon Hybrid Bolaamphiphiles.
B.Yu, Y.Z.Hui,Chin. J. Chem.,1996,14(2),171-179
15. Structural Study on a Bioactive Fructan from the Root ofAchyranthes Bidentata Blume.
B.Yu, G.Y.Tian, Y.Z.Hui,Chin. J. Chem.,1996,13(6),539-544
16. A One-Step Procedure for Facile, Selective Synthesis of Protected D-Glucopyranosides with Free 2-C Hydroxyl Group Starting from Peracetylated b-D-Glucopyranose.
; M.Z.Liu, H.N.Fan, Z.W.Guo, Y.Z.Hui,Chin. J. Chem.,1996,14(2),190-192
17. One-Step Glycosylation and Selective Deprotection of Peracetylated Monosaccharides for Facile Syntheses of Allyl Glycosides with a Free C-2 Hydroxyl Group.
M.Z.Liu, H.N.Fan, Z.W.Guo, Y.Z.Hui,Carbonhydr. Res.,1996,290, 233-237
18. A New Reaction for One-pot, Selective Mono-O-Glycosylations of 9,10- Dihydroxyphenanthrene Under Mild Conditions.
Z.W.Guo, Y.Z.Hui,Chin.Chem.Lett.,1996,7(5),423-424
19. Isolation and Structure Elucidation of a Polysaccharide with Radiation-Protective Activity fromSpinulina Platensis.
Z.W.Guo, Y.Z.Hui,Chin.J. Chem.,1996,14(3),279-285
20. A One-Step Procedure for Facile Preparation of D-Glucopyranosides with a Free 2-OH from Peracetylated b -D-Glucopyranose.
M.Z.Liu, H.N.Fan, Z.W.Guo, Y.Z.Hui,J. Carbohydr. Chem.,1996,15(9),1139-1145
21. The Stereospecific Synthesis of Mixed-acid Phospholipids with Polyunsaturated Fatty Acid from D-mannitol.
J. Xia, Y. Z. Hui,Tetrahedron: Asymmetry, 1997,3, 451-485
22. Recent Progress of Saponin Research.
M.Z.Liu, Z.W.Guo, Y.Z.Hui,Natural Product Research and Development, 1997,9(2), 81-85
23. A Facial Regioselective 1,6-O-Diacetylation Method of Methyl glycopyranosides and Their Dimethyl Phosphonates.
G.T.Zhang, Z.W.Guo, Y.Z.Hui,Synth. Commun., 1997,27(11), 1907-1918
24. First Total Synthesis of Tricolorin A.
S.F.Lu, Q.Q.Ouyang, Z.W.Guo, B.Yu, Y.Z.Hui,Angew. Chem. Int. Ed. Engl., 1997, 36, 2344-2346.
25. A Synthesis of Tricolorin A.
S.F.Lu, Q.Q.Ouyang, Z.W.Guo, B.Yu, Y.Z.Hui,J.Org.Chem., 1997, 62, 8400-8405.
26. Synthesis and Antitumor Activities of Diosgenyl Glycosides.
M.Z.Liu, B.Yu, Z.W.Guo, C.Li, Y.Z.Hui,Carbohydr. Lett., 1997, 2,423-428.
27. Conformational Analysis of Two Diosgenyl Saponins.
M.Z.Liu, B.Yu, M.B.Chen, C.L.Feng, Y.Z,Hui,Chin. Chem. Lett., 1997, 8, 785-788.
28. A New Method for the Cleavage of Carbohydrate Benzylidene Acetyl by Ceric (IV) Ammonium Nitrate in CH3CN-H2O (10:1).
S.F.Lu, Q.Q.Ouyang, Z.W.Guo, B.Yu, Y.Z.Hui,Chin. Chem. Lett., 1997, 8, 841.
29. Efficient One-Step Methyl Esterification of Carboxylic Acid and Deacetylation by BF3OEt2-MeOH.
S.F.Lu, Q.Q.Ouyang, Z.W.Guo, B.Yu, Y.Z.Hui,Chin. Chem. Lett., 1997, 8, 843.
30. What is the Sugar Chains¡¯ Function in Saponin.
M.Z.Liu, Z.W.Guo, Y.Z.Hui,Youji Huaxue, 1997, 17, 307.
31. Recent Progress on Resin Glycoside Research.
S.F.Lu, Q.Q.Ouyang, Z.W.Guo, Y.Z.Hui,Youji Huaxue, 1997,17(4), 1[3]
