出生年月:1978年4月
职称:副教授
简历:
教育经历:
1999年6月复旦大学生命科学学院理科基地班本科毕业;
2004年6月复旦大学生命科学学院生理学和生物物理学系生物物理学专业博士毕业,2005年6月获复旦大学理学博士学位;
工作经历:
2004年7月起在复旦大学生命科学学院生理学和生物物理学系任教,2004年12月认定为讲师,2007年11月晋升副教授。
主持科研项目:
2006.1-2008.12 国家自然科学基金:脂筏特征蛋白flotillin的结构、功能及其与2型糖尿病关系的研究(项目批准号:30500113)
主要参与科研项目:
2007.1-2009.12 国家自然科学基金:人红细胞中精氨酸酶和膜的相互作用及其与2型糖尿病关系的研究(项目批准号:30670499)
2007.1-2009.12 国家自然科学基金:限制性内切酶Sau3AI的结构与功能研究(项目批准号:30600107)
主要研究方向:
脂筏相关蛋白的结构与功能研究
新型荧光蛋白的结构与拓展应用研究
获奖情况:
2007年获复旦大学复华奖教金青年教师成才奖
代表性论文和专著:
(* for the corresponding author)
[1] W.H. Jiang,Y. Ding, X.J. Hu, F. Peng, H.Q. Zhou, Z.H. Zhang*, Effect on membrane transport in the erythrocytes by band 3 cross-linking. Chin Sci Bull 47 1889-1892. (2002)
[2]Y. Ding, W. Jiang, Y. Su, H. Zhou, Z. Zhang*, Expression and purification of recombinant cytoplasmic domain of human erythrocyte band 3 with hexahistidine tag or chitin-binding tag in Escherichia coli. Protein Expr Purif 34 167-175. (2004)
[3]Y. Ding, M. Jiang, W. Jiang, Y. Su, H. Zhou, X. Hu, Z. Zhang*, Expression, purification, and characterization of recombinant human flotillin-1 in Escherichia coli. Protein Expr Purif 42 137-145. (2005)
[4] M. Jiang,Y. Ding, Y. Su, X. Hu, J. Li, Z. Zhang*, Arginase-flotillin interaction brings arginase to red blood cell membrane. FEBS Lett 580 6561-6564. (2006)
[5] W. Jiang1,Y. Ding1, Y. Su, M. Jiang, X. Hu, Z. Zhang*, Interaction of glucose transporter 1 with anion exchanger 1 in vitro. Biochem Biophys Res Commun 339 1255-1261. (2006) (1: contributed equally)
[6] Y. Su,Y. Ding, M. Jiang, W. Jiang, X. Hu, Z. Zhang*, Associations of protein 4.2 with band 3 and ankyrin. Mol Cell Biochem 289 159-166. (2006)
[7] F. Yu, J. Song, C. Xu,Y. Ding, X. Hu*, J. He*, Z. Zhang, Crystallization and preliminary X-ray analysis of Sau3AI C-terminal 232-419 amino acids fragment. Protein Pept Lett 13 627-628. (2006)
[8] S. Jiao, Z. Liu, W.H. Ren,Y. Ding, Y.Q. Zhang, Z.H. Zhang, Y.A. Mei*, cAMP/protein kinase A signalling pathway protects against neuronal apoptosis and is associated with modulation of Kv2.1 in cerebellar granule cells. J Neurochem 100 979-991. (2007)
[9] Y. Su,Y. Ding, M. Jiang, X. Hu, Z. Zhang*, Protein 4.2 Komatsu (D175Y) associated with the lack of interaction with ankyrin in human red blood cells. Blood Cells Mol Dis 38 221-228. (2007)
[10] C. Xu, J. Song,Y. Ding, F. Yu, L. Sun, L. Tang, X. Hu*, Z. Zhang, J. He*, Crystallization and preliminary X-ray analysis of Sau3AI/E64A mutant protein. Protein Pept Lett 14 505-506. (2007)
[11] Y. Zhou, J. Song, L. Weng, X. Hu,Y. Ding*, Z. Zhang, Expression, purification, crystallization and preliminary x-ray analysis of Cyan fluorescent protein CyPet. Protein Pept Lett 14 928-932. (2007)
[12] Y. Wu, Y. Zhou, J. Song, X. Hu,Y. Ding*, Z. Zhang, Using green and red fluorescent proteins to teach protein expression, purification, and crystallization. Biochem Mol Biol Edu 36 43-54. (2008)
[13] Y. Zhou, Y. Wu, J. Song,Y. Ding*, X. Hu*, Z. Zhang, Crystallization and preliminary X-Ray analysis of fluorescent protein mBanana. Protein Pept Lett 15 113-114. (2008)