潘宪明

王朝百科·作者佚名  2010-02-16
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潘宪明 博士

教授,博导,国家杰出青年基金获得者

1978-1981年,复旦大学 学士

1982-1984年,北京大学 硕士

1986-1989年,德国Bochum大学 博士

现任清华大学教授

主要科研领域与方向:生物化学,蛋白质折叠和蛋白质结构预测。

Selected Publications Sheng X. R., Zhang H. J., Pan X. M. and Zhou J.M. (1997) Domain movement in rabbit muscle adenylate kinase might involve proline isomerization. FEBS Letters, 413, 429-432.

■ Zhang H. J., Sheng X. R., Pan X. M.* and Zhou J.M. (1997) Activation of adenylate kinase by denaturatants is due to the increasing flexibility at its active sites. BBRC, 238, 382-386.

■ Zhang H. J., Sheng X. R., Niu W. D., Pan X. M.* and Zhou J.M. (1998) Rabbit Muscle Adenylate Kinase: Evidence for at Least Two Native forms in Equilibrium in Aqueous Solution. J. Biol. Chem., 273, 7448-7456.

■ Zhang H. J., Sheng X. R., Pan X. M.* and Zhou J. M. (1998) Refolding of urea-denatured adenylate kinase. Biochem. J., 333, 401-405.

■ Sheng X. R., Li X. and Pan X. M.* (1999) An Iso-random Bi Bi mechanism for adenylate kinase. J. Biol. Chem., 274, 22238-22243.

■ Li X. and Pan X. M.* (2001) New Method for accurate prediction of solvent accessibility from protein sequence. Proteins, structure, Function, and Genetics, 42, 1-5.

■ Pan X. M.* (2001) Multiple linear regression for protein secondary structure prediction. Proteins, structure, Function, and Genetics. 43,256-9

■ Li X., Yang Han and Pan X. M.*(2001) Cysteine-25 of adenylate kinase reacts with dithiothreitol to form an adduct upon aging of the enzyme. FEBS Letters, 507 (2) 169-173.

■ Han Y. , Li X. and Pan X. M.*(2002) Native States of adenylate kinase are two active sub-ensembles. FEBS Letter, 528 161-165

■ Xu S., Qin S. and Pan X. M.* (2004)Thermal and Conformational Stability of Ssh10b Protein from Archaeon Sulfolobus shibattae. Biochem. J, 382, 433-440.

 
 
 
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