通用名称：坎地沙坦
英文名称：Candesartan
中文别名：坎地沙坦环己氧羰氧乙酯
英文别名：Atacand、Candesartan Cilexetil、Candesartan Hexetil
【适应症】
1.Candesartan is in a class of drugs called angiotensin II receptor antagonists. Candesartan prevents the constriction (narrowing) of blood vessels (veins and arteries).
2.Candesartan is used to treat high blood pressure (hypertension).
3.Candesartan may also be used for purposes other than those listed in this medication guide.
【用法用量】
1.Take candesartan exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
2.Take each dose with a full glass (8 ounces) of water.
3.You can take candesartan with or without food.
4.Do not stop taking candesartan unless your doctor approves. If you stop taking your medication, your condition could become much worse.
5.Store candesartan at room temperature away from moisture and heat.
【注意事项】
1.Do not take candesartan if you are pregnant or planning a pregnancy. When used during the second and third trimesters of pregnancy, candesartan can cause injury and even death to the developing fetus. Notify your doctor immediately if you think you might be pregnant.
2.Use caution when driving, operating machinery, or performing other hazardous activities. Rarely, candesartan may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Also use caution when rising from a sitting or lying position.
3.Use alcohol cautiously. Alcohol may further lower blood pressure and increase drowsiness and dizziness while you are taking candesartan.
If Miss a Dose: 1.Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.
Contraindications: 1.Before taking candesartan, tell your doctor if you
*have kidney disease;
*have liver disease;
*are on a salt-restricted diet or have high levels of potassium in your blood; or
*are taking potassium supplements (e.g., K-Dur, Klor-Con, others), or a potassium-sparing diuretic such as amiloride (Midamor), triamterene (Dyrenium, Dyazide, Maxzide), or spironolactone (Aldactone).
2.You may not be able to take candesartan, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
3.Candesartan is in the FDA pregnancy category D. This means that it is known to harm an unborn baby. When used during the second and third trimesters of pregnancy, candesartan can cause injury and even death to the developing fetus. Do not take candesartan if you are pregnant.
4.It is not known whether candesartan passes into breast milk. Do not take candesartan without first talking to your doctor if you are breast-feeding a baby.
Special Concerns: 1.Use caution when driving, operating machinery, or performing other hazardous activities. Rarely, candesartan may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Also use caution when rising from a sitting or lying position.
2.Use alcohol cautiously. Alcohol may further lower blood pressure and increase drowsiness and dizziness while you are taking candesartan.
3.Do not use salt substitutes or take potassium supplements without first talking to your doctor. Candesartan can affect potassium levels in your body.
【不良反应】
1.If you experience any of the following serious side effects, stop taking candesartan and call your doctor immediately or seek emergency medical treatment.
*an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives); or
*little or no urine.
2.Other side effects are less serious. Continue to take candesartan and talk to your doctor if you experience
*headache,
*dizziness,
*fatigue,
*diarrhea or upset stomach,
*muscle or joint pain or cramps,
*insomnia, or
*congestion or cough.
3.Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
【相互作用】
1.Before taking candesartan, tell your doctor if you
*take a potassium supplement such as K-Dur, Klor-Con, and others;
*take a potassium-sparing diuretic (water pill) such as amiloride (Midamor), spironolactone (Aldactone), or triamterene (Dyrenium, Dyazide, Maxzide); or
*use a salt substitute.
2.Candesartan can affect potassium levels in your body. You may not be able to take candesartan, or you may require a dosage adjustment or special monitoring if you are taking any of the medicines listed above.
3.Tell your doctor about any other medicines you take to treat high blood pressure or other heart conditions. Candesartan may cause very low blood pressure if it is taken with other heart medications.
4.Drugs other than those listed here may also interact with candesartan or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.
【药物过量】
1.Seek emergency medical attention.
2.Symptoms of a candesartan overdose are not well known but might include dizziness, weakness, fainting, and fatigue.
