Enantiocontrolled Synthesis of Fluoro-Organic Compounds: Stereochemical Challenges and Biomedical Targets

基本信息出版社:John Wiley & Sons精装:690页正文语种:英语ISBN:0471973726条形码:9780471973720商品尺寸:23.1 x 15.7 x 4.1 cmASIN:0471973726商品描述Written by a leading expert in the field, this is a comprehensive review of the methods for preparing stereochemically defined fluorine-containing compounds of biomedical importance. Fluorinated organic compounds are well known for their unusual reactivity but the growing importance of these compounds in the biomedical field has been accompanied by an increasing awareness of the necessity to synthesise and explore the biological properties of stereochemically defined fluoro-compounds. This is the first book written on this exciting area of research. It contains: * detailed reviews on stereocontrolled synthesis of biologically important compounds * 21 chapters covering the main areas of asymmetric synthesis and biocatalysts where fluorine plays a key role * mechanisms and methods for synthesizing fluoro-organic compounds Written for professionals involved in organic, physical and organofluorine chemistry, natural product synthesis, biological, pharmaceutical and other life science related industries.