生物工程导论INTRODUCTION TO BIOENGINEERING
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作者： Y. C. Fung著
出 版 社： Pengiun Group (USA)
出版时间： 2001-12-1字数：版次： 1页数： 291印刷时间： 2001/05/01开本：印次： 1纸张： 胶版纸I S B N ： 9789810243982包装： 平装内容简介
Bioengineering is attracting many high quality students. This invaluable book has been written for beginning students of bioengineering, and is aimed at instilling a sense of engineering in them.
Engineering is invention and designing things that do not exist in nature for the benefit of humanity. Invention can be taught by making inventive thinking a conscious part of our daily life. This is the approach taken by the authors of this book. Each author discusses an ongoing project, and gives a sample of a professional publication. Students are asked to work through a sequence of assignments and write a report. Almost everybody soon realizes that more scientific knowledge is needed, and a strong motivation for the study of science is generated. The teaching of inventive thinking is a new trend in engineering education. Bioengineering is a good field with which to begin this revolution in engineering education, because it is a youthful, developing interdisciplinary field. --This text refers to the Hardcover edition.
作者简介：
Y. C. Fung works on solid mechanics, and has helped to establish the fields of aeroelasticity and biomechanics.He received his BS and MS from the National Central University in China and PhD from the California Institute of Technology. He received the United States Presidential National Medal of Science in the year 2000, and the Founders Award of the US National Academy of Engineering in 1998. He was elected a member of the US National Academy of Science in 1992, the US Institute of Medicine in 1991, the US National Academy of Engineering in 1979, the Academy of Science of China in 1994, and the Academia Sinica in 1966. He is Distinguished Alumnus of Caltech, Honorary Member of ASME, and winner of the von Karman Medal (ASCE),Timoshenko Medal (ASME), Poiseuille Medal (ISB), Borelli Medal (ASB), Landis Award (AMS), and Alza Award (BMES).
目录
Preface
Table of Contents
To the Instructor
To the Students
Sample Assignments
1. Roles of Flow Mechanics in Vascular Cell Biology in Health and Disease
Shu Chien
Paper: Chiu, J. J., D. L. Wang, S. Chien, R. Skalak and S. Usami. Effects of
disturbed flows on endothelial cells. J. Biomech. Eng. 120: 2-8, 1998, by
permission.
2. Perspectives of Biomechanics
Yuan Cheng Fung
Paper: Fung, Y. C. Pressure, flow, stress, and remodeling in the pulmonary
vasculature. In: The Pulmonary Circulation and Gas Exchange, edited by
W. W. Wagner and E. K. Weir. Futura Pub. Co., pp. 343-364, 1994, by
permission.
3. The Implantable Glucose Sensor: An Example of Bioengineering Design
David A. Gough
Paper: Gough, D. A., J. Y. Lucisano and P. H. S. Tse. Two-dimensional
enzyme electrode sensor for glucose. Analytical Chemistry, 57: 2351-2357,
1985, by permission.
4. Design and Development of Artificial Blood
Marcos Intalietta
Paper: Tsai, A. G., B. Friesenecker, M. C. Mazzoni, H. Kerger, D. G. Buerk,
P. C. Johnson and M. Intaglietta. Microvascular and tissue oxygen gradients
in the rat mesentery. Proc. Natl. Acad. Sci. USA. 95: 6590-6595, 1998, by
permission.
5. Analysis of Coronary Circulation: A Bioengineering Approach
Ghassan S. Kassab
Paper: Kassab, G. S., J. Berkley and Y. C. Fung. Analysis of pig's coronary
arterial blood flow with detailed anatomical data. Ann. Biomed. Eng. 25:
204-217, 1997, by permission.
6. What Lies Beyond Bioinformatics?
Bernhard Palsson
Paper: Schilling, C. H., J. S. Edwards and B. O. Palsson. Toward metabolic
phenomics: Analysis of genomic data using flux balances. Biotechnol. Prog.
15: 288-295, 1999, by permission.
Paper: Edwards, J. S. and B. O. Palsson. The Escherichia coli MG1655 in
silico metabolic genotype: Its definition, characteristics, and capabilities.
PNAS 97: 5528-5533, 2000, by permission.
7. Tissue Engineering of Articular Cartilage
Robert L. Sah
Paper: Reindel, E. S., A. M. Ayroso, A. C. Chen, D. M. Chun, R. M. Schinagl
and R. L. Sah. Integrative repair of articular in vitro: Adhesive strength of
the interface region. J. Orth. Res. 13: 751-760, 1995, by permission.
8. Cell Activation in the Circulation
Geert W. Schmid-Schonbein
Paper: Mazonic, M. C. and C. W. Schmid-SchSnbein. Mechanisms and
consequences of cell activation in the microcirculation. Cardiovas. Res. 32:
709-719, 1996, by permission.
Paper: Mitsuoka, H., E. B. Kistler and G. W. Schmid-SchSnbein. Generation
of in vivo activating factors in the ischemic intestine by pancreatic enzymes.
PNAS 97: 1772-1777, 2000, by permission.
9. Molecular Basis of Cell Membrane Mechanics
Lanping Amy Sung
Paper: Sung, L. A., S. Chien, L. S. Chang, K. Lambert, S. A. Bliss,
E. E. Bonhassion, R. L. Nagel, R. S. Schwartz and A. C. Rybicki. Molecular
cloning of human protein 4.2: A major component of the erythrocyte
membrane. Proc. Natl. Acad. Sci. 87: 955-959, 1990, by permission.
10. Biomechanics of Injury and Healing
Pin Tong and Yuan Cheng Fung
Paper: An Editorial Article by Savio L.-Y. Woo: The importance of
biomechanics for the new millennium. J. Orth. Sc. 5: 89-91, 2000, by
permission.
Paper: Yen, R. T., Y. C. Fung, H. H. Ho and G. Butterman. Speed of stress
wave propagation in Lung. J. Appl. Physiol. 61: 701-705, 1986, by
permission.
Paper: Fung, Y. C., R. T. Yen, Z. L. Tao and S. Q. Liu. A hypothesis on the
mechanism of trauma of lung tissue subjected to impact load. J. Biomech.
Eng. 110: 50-56, 1988, by permission.
11. Pulsatile Blood Flow in the Lung Studied as an Engineering System
Michael R. T. Yen and Wei Huang
Paper: Huang, W., Y. Tian, J. Gao and R. To Yen. Comparison of theory
and experiment in pulsatile flow in cat lung. Ann. Biomed. Eng. 26:
812-820, 1998, by permission.
Appendixes
A. About the Authors
B. About the Department of Bioengineering at the University of California, San Diego
Farewell to Students