心血管病治疗:《Braunwald心脏病学》配套Cardiovascular Therapeutics

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作者: Elliott M. Antman 著

出 版 社: Oversea Publishing House

出版时间: 2006-12-1字数:版次: 1页数: 949印刷时间: 2006/12/01开本: 大16开印次: 1纸张: 胶版纸I S B N : 9781416033585包装: 精装编辑推荐

"This multi-author book contains comprehensive information on cardiovascular therapeutics, a rapidly changing field. Dr Antman is to be congratulated for bringing together 112 experts in their respective fields who collectively contribute 55 chapters. All aspects of cardiovascular therapeutics are covered." Circulation

内容简介

This companion to Braunwald's Heart Disease equips you with all of today's most effective therapeutic guidelines and management solutions for the full range of heart disease patients. It reflects the most recent standards for drug management as well as the latest in new technologies. Reorganized to mirror your changing practice, each cardiovascular-problem-based section offers a chapter on pharmacologic treatment (with a minimum of pathophysiology)...a chapter on catheter-based or minimally invasive interventions...and a discussion of surgical options. You'll also find a brand-new chapter on gene therapy and stem cell therapy, plus new chapters on many other rapidly developing areas of practice. The result is an outstanding single-volume source for state-of-the-art, clinically oriented guidance on both common and unusual areas of cardiovascular treatment.

Facilitates the decision-making process clinicians face when choosing among various cardiovascular therapeutic options.

covers the latest concepts in pathophysiology, evaluation, and management of patients with cardiovascular disorders

Addresses pharmacological, interventional, and surgical management approaches for each type of cardiovascular disease, putting advice on the full range of therapeutic options at your disposal.

Keeps you current with brand-new chapters on gene therapy and stem cell therapy * unstable and chronic stable angina * management of unstable angina and non-ST-elevation myocardial infarction * devices for heart failure and arrhythmias * prevention of ischemic disease * the regulatory approval process for new cardiovascular drugs and devices * and more.

Delivers a fully revised section on "Heart Failure" that explores cardiac resynchronization therapy, surgical interventions, ambulatory management, hospital management, and cardiac transplantation and circulatory support devices.

Offers a completely updated section on "Other Cardiovascular Conditions" that addresses issues such as pharmacologic treatment of cardiovascular disease during pregnancy * care for adults with congenital heart disease * treatment of primary pulmonary hypertension * prevention and treatment of infective endocarditis * treatment of pericardial disease * and rehabilitation of the patient with cardiovascular disease.

Reflects a new emphasis on the role of diet and exercise in the management of cardiovascular problems in conformity with ACC/AHA/ESC guidelines.

目录

Color Plates follow page xxiv.

SECTION 1 Decision-Making and Therapeutic Strategies in Cardiovascular Medicine

1. Tools for Assessment of Cardiovascular Tests and Therapies

Elliott M. Antman, Robert M. Califf, and

Joel Kupersmith

Interpretation of Diagnostic Tests

Clinical Trials

How to Read and Interpret a Clinical Trial

Meta-Analysis

Cost-Effectiveness Analysis

2. The Use of Cardiovascular Drugs: Pharmacological Principles, 35

Stanley Nattel

Pharmacokinetic Factors

Oral Bioavailability (F)

Volume of Distribution

Protein Binding

Elimination and t1/2

Pharmacodynamic Factors

Dose

Drug Interactions

Pharmacogenomics

3. Gene Therapies and Stem Cell Therapies

Gene Therapies for Cardiovascular Diseases: Where We Are and Where We Are Going

Luis G. Melo, Christopher A. Ward, and Victor J. Dzau Overview

Gene Therapies for Myocardial Protection

Gene Therapies for Myocardial Rescue

Gene Therapies for Vascular Protection

Clinical Gene Therapy

Perspectives and Future Directions

Stem Cell Therapy for Cardiovascular Disorders

Kai C. Wollert and Helmut Drexler

Potential Donor Cells

Modes of Cell Delivery

Clinical Application of Stem Cell Therapy

Coronary Artery Disease with No Mechanical Revascularization Option

Ischemic Cardiomyopathy, Chronic Heart Failure

The Foreseeable Future of Cardiovascular Stem Cell Therapy

4. The Process of Regulatory Review for New Cardiovascular Devices

Neal L Muni and Brain D. Zuckerman

Regulatory History of the Device Review Process

The Temple Report and Evolution of the Device Regulatory

Process

Risk, Benefit, and the Product Life Cycle

Ensuring the Safety of Marketed Devices

Conclusion

SECTION 2 Ischemic Heart Disease

5. Pharmacologic Options for Treatment of Ischemic Disease

Jonathan Abrams, John Schroeder, William 14. Frishman, and lane Freedman

The Organic Nitrates

Calcium Channel Blockers

β-Adrenergic Blockers

Thrombosis and Ischemic Cardiovascular Disease

Thrombosis: Future Directions

6. Mechanical Approaches to Percutaneous Coronary Intervention

Jahuna Karha, A. Michael Lincoff, and Stephen G. Ellis

Coronary Angioplasty

Other Devices

Intravascular Imaging Techniques

Summary

7. Treatment with Drug-Eluting Stents

George D. Dangas

Drug-Eluting Stent System

Results of Main Clinical Trials of Approved DES

Clinical Use of DES in Different Patient and Clinical Subsets

In-Stent Restenosis

DES Thrombosis

Adjunctive Pharmacologic Therapy

Future Directions

8. Revascularization Options for Ischemic Heart Disease:

Coronary Artery Bypass Grafting and Percutaneous

Coronary Intervention

Oon C. Ooi, Charles J. Mullany, and Charanjit S. Rihal

Effectiveness of Revascularization: CABG

Effectiveness of Revascularization: PCI

Relative Benefits of PCI and CABG

……

SECTION 3 heart Failure

SECTION 4 Arrhythmias/Conduction Disturbances

SECTION 5 Dyslipoproteinemias/Atherosclerosis

SECTION 6 Hypertension

SECTION 7 Other Cardiovascular Conditions

APPENDIX 1

APPENDIX 2

APPENDIX 3

 
 
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