Central pain syndrome中枢性疼痛综合症
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作者： Sergio Canavero，Vincenzo Bonicalzi著
出 版 社：
出版时间： 2007-1-1字数：版次：页数： 382印刷时间： 2007/01/01开本： 16开印次：纸张： 胶版纸I S B N ： 9780521866927包装： 精装内容简介
Central Pain Syndrome is a neurological condition caused by damage specifically to the central nervous system - brain, brainstem, or spinal cord. This is the only up-to-date book available on the clinical aspects (including diagnosis and therapy) of CPS management. The authors have developed a very complete reference source on central pain, which includes background material, pathophysiology, and diagnostic and therapeutic information. A medical mystery for 100 years with no effective cure, this book turns the concept of incurability of central pain on its head, providing a rational approach to therapy based on a rational theory.
作者简介：
Sergio Canavero is the founder of Turin Advanced Neuromodulation Group, a think tank focused on the advancement of neuromodulation.
Vincenzo Bonicalzi is a senior staff member at the Department of Neurosciences at the third largest medical facility in Italy.
目录
List of Tables
Preface (or, the Story of an Idea)
1 Introduction
Definitions
History
2Central Pain of Brain Origin
Epidemiology and clinical features
1. Lesions causing CP and location
2. Incidence and prevalence
3. Age of onset of CPSP
4. Sex distribution of CPSP
5. Time to pain onset
6. Side of the lesions
7. Size of the lesion and CPSP
8. Pain distribution
9. Quality of pain
10. Intensity of pain
11. Components
12. Evoked pains
13. Somatosensory findings
14. Sympathetic and other signs and symptoms
Special considerations
1. Sensory epilepsy
2. Parkinson's disease (PD)
3. Iatrogenic lesions
3 Central Pain of Cord Origin
1. Lesions causing CCP
2. Incidence and prevalence
3. Age of onset and sex distribution
4. Time to pain onset
5. Level of lesion
6. Distribution of pain
7. Quality
8. Intensity
9. Components
10. Evoked pains
11. Somatosensory deficits
12. Sympathetic and other signs and symptoms
13. Course
Special considerations
1. Syringomyelia
2. Multiple sclerosis (MS)
3. Spinal epilepsy
4 Diagnosing Central Pain
5 Drug Therapy
Oral and parenteral drug therapy
1. General comments
GABA drugs
Antiglutamatergic agents
Sodium channel blockers
Antidepressants
Opioids, naloxone and cannabinoids
Miscellaneous agents
Combinations
2. Drug aggravation of CP
6Neuromodulation
Electrical
1. Extra- and subdural motor (MCS) and sensory cortex stimulation (PCS)
Mechanism of action
2. Deep brain stimulation (DBS)
Mechanism of action
a. PAG-PVG
b. Vc
c. Other areas
Efficacy
a. Vc DBS
b. PAG-PVG DBS
3. Spinal cord stimulation
Mechanism of action
Efficacy
……
7 Pathophysiology:Human Data
8 Piecing Together the Evidence
References
Index
