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　　分類: 图书,进口原版书,科学与技术 Science & Techology ,

作者： Mei-Ling Ting Lee著

出 版 社：

出版时间： 2004-4-1字数：版次： 1页数： 371印刷时间： 2004/04/01开本： 16开印次： 1纸张： 胶版纸I S B N ： 9780792370871包装： 精装内容简介

After genomic sequencing, microarray technology has emerged as a widely used platform for genomic studies in the life sciences. Microarray technology provides a systematic way to survey DNA and RNA variation. With the abundance of data produced from microarray studies, however, the ultimate impact of the studies on biology will depend heavily on data mining and statistical analysis. The contribution of this book is to provide readers with an integrated presentation of various topics on analyzing microarray data.

目录

List of figures

List of tables

Preface

Part I Genome probing using microarrays

1 Introduction

2 DNA, RNA, proteins, and gene expression

3 Microarray technology

4 Inherent variability in array data

5 Background noise

6 Transformation and normalization

7 Missing values in array data

8 Saturated intensity readings

Part II Statistical models and analysis

9 Experimental design

10 ANOVA models for microarray data

11 Multiple testing in microarray studies

12 Permutation tests in microarray data

13 Bayesian methods for microarray data

14 Power and sample size considerations

Part III Unsupervised exploratory analysis

15 Cluster analysis

16 Principal components and singular value decomposition

17 Self-organizing maps

Part IV Supervised learning methods

18 Discrimination and classification

19 Artificial neural networks

20 Support vector machines

Glossary of Notation

Author Index

Topic Index

 

 

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