这是一个关于在全世界有些人发现他们拥有某些不同寻常的超能力之后去尝试用这些能力去改变他们生活的故事。
主要人物设定为：
一位印度的遗传学教授，自从他的父亲失踪后，他赶到了纽约，并且开始探索一种神秘理论－－普通人当中也许有人拥有超能力。
一个梦想家，他试图劝说自己的政客兄弟相信自己能飞。
一个高中啦啦队长，发现自己竟然刀枪不入。
一个拉斯维加斯的脱衣舞女，发现自己竟然能瞬间移动，同时往返于两个不同地点。
一个囚犯醒来的时候发现自己竟神秘地来到了高墙之外。
一个有天赋的画家，毒品毁了他的生活和他与女友的关系，却发现自己能描绘未来的景象。
一个在别人看来纯粹依靠运气办案的警察，实际上拥有读心术。
在日本，一个年轻人可以纯粹依靠意念力来使时间停止。
Heroes is a serial saga about people all over the world discovering that they have superpowers and trying to deal with how this change affects their lives. The relatable superheroes include Peter Petrelli, a 30-year-old male nurse who believes can fly, Diego Medina, a 28-year-old junkie who has the ability to paint images of the future when he is high, Niki Sanders, a 33-year-old Las Vegas showgirl who can do incredible things with mirrors, Hiro Makamura, a 24-year-old Japanese comic-book geek who literally makes time stand still, D.L. Hawkins, a 31-year-old inmate who can transport himself through walls, Matt Parkman, a beat cop who can hears other people's thoughts, and Claire Bennet, 17-year-old cheerleader who defies death at every turn. Not only are they discovering what having superpowers means to them but also the larger picture of where their superpowers come from. Eventually their .