流感快速参考（第2版）：Rapid Reference to Influenza
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作者： Jan Wilschut 著
出 版 社： Oversea Publishing House
出版时间： 2006-6-1字数：版次： 1页数： 240印刷时间： 2006/06/01开本： 64开印次： 1纸张： 胶版纸I S B N ： 9780723434337包装： 平装编辑推荐
作者简介：
Jan C Wilschut,PhD is Professor of Molecular Virology in the Department of Medical Microbiology at the University Medical Centre, Groningen, The Netherlands. His main research interests include the cell entry mechanisms of enveloped viruses, influenza virus and alpha- and flaviviruses in particular, and viral and tumour vaccine development. Based on his interest in viral membrane fusion processes, he developed the virosome system as a basis for novel vaccine modalities. He is Co-ordinator of the Netherlands Influenza Vaccine Research Centre (NIVAREC) and has published over 150 papers in international peer-reviewed journals.
内容简介
The ongoing threat of pandemic influenza is very serious indeed as evidenced by recent articles within The Lancet and The Lancet Infectious Disease. This title provides the reader with authoritative and accessible information on the subject of influenza. Clearly written by key experts in the field and highly illustrated in full colour, the book provides an overview of influenza, its pathogenesis, epidemiology, the burden of disease and its health economics. Rapid Reference Influenza also summarises available information on the molecular biology of influenza and the emergence of new influenza viruses. Completely updated with the latest information on H5N1, the book aims to contribute to international efforts to emphasize the major burden of influenza and the need for better control.
Expert information succinctly written for ease of use.
Abundant use of bulleted lists and short tables, for quick access to comparative information.
Presents evidence-based sources for practice when available, either through research or best-practice guidelines.
Completely up-to-date in light of the H5N1 emergence and spread.
Useful addresses and websites appendix provide additional resources for the physician.
Updated epidemiology regarding H5N1.
Revised discussion about the relevance of the potential impact of H5N1.
Latest statistics from the World Health Organization.
Upda te on 'pandemic preparedness' and related issues including new vaccine development.
Includes an overview of current 'global thinking' about the possible pandemic including reports from the recent meeting between the WHO and the World Bank.
目录
Biographies
Foreword
Foreword to the first edition
Acknowledgements
Abbreviations
1.Introduction
The influenza virus
Pandemics and epidemics
Clinical picture and impact of flu
Prevention and control
References
2.The Influenza Virus: Structure and Replication
Classification and nomenclature of influenza viruses
Influenza virus structure
Virus replication
References
3.Influenza Epidemics and Pandemics
Annual influenza epidemics
Origin of influenza pandemics
Influenza pandemics of the past
Will there be a new pandemic?
Influenza pandemic preparedness
Concluding remarks
References
4.The Immune Response to Influenza Infection
The innate immune response
Initiation of the adaptive immune response
Effector mechanisms of the adaptive response
Effect of ageing on the immune system
References
5.Pathogenesis, Clinical Features and Diagnosis
Pathogenesis of influenza
Presentation of uncomplicated influenza
Complications of influenza
Influenza in susceptible subgroups
Diagnosis of influenza
References
6.Social and Economic Impact of Influenza
Social impact
Economic impact
Impact of pandemic influenza
References
7.Antivirals: Treatment, Prophylaxis and Pandemic Control
Mechanisms of action of antivirals
Antivirals in treatment and prophylaxis of influenza
Development of drug resistance
The role of antivirais in pandemic control
References
8.Vaccination: Cornerstone of Influenza Control
Current inactivated influenza vaccines
Vaccination coverage
Benefits of influenza vaccination
How may influenza control be further improved?
References
9.Vaccination: Novel Developments and Pandemic Vaccines
Novel inactivated influenza vaccines with
improved efficacy
Mucosal delivery of influenza vaccines
Novel approaches to vaccine virus production
Pandemic vaccines
References
Appendix 1-Useful Websites
Appendix 2-WHO Global Agenda for Influenza Surveillance and Control
Appendix 3-Position Paper on Influenza Vaccines
Appendix 4-Avian Influenza: Assessing the Pandemic Threat
Index
