有机药学与制药Organic Medicinal and Pharmaceutical
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作者： John Block著
出 版 社： Oversea Publishing House
出版时间： 2003-12-1字数：版次： 1页数： 991印刷时间： 2003/12/01开本： 16开印次： 1纸张： 铜版纸I S B N ： 9780781734813包装： 精装内容简介
For over half a century, this book has served the discipline of medicinal chemistry for both graduate and undergraduate pharmacy and chemistry students as well as practicing pharmacists. Fully updated for the Eleventh Edition, coverage begins with the fundamental principles of chemistry, biochemistry, and biology that underlie the discipline of medicinal chemistry. These principles are then applied to understanding the properties, mode of action, therapeutic applications, and limitations of various pharmaceutical agents. The subject matter is organized by pharmaceutical and therapeutic classes, providing a bridge between the basic sciences and clinical practice. The text contains many tables for quick reference to names, formulations, dosages, and applications.
目录
Preface
Contributors
CHAPTER 1 Introduction
CHAPTER 2 Physicochemical Properties in Relation to Biological Action
CHAPTER 3 Combinatorial Chemistry
CHAPTER 4 Metabolic Changes of Drugs and Related Organic Compounds
CHAPTER 5 Prodrugs and Drug Latentiation
CHAPTER 6 Biotechnology and Drug Discovery
CHAPTER 7 Immunobiologicals
CHAPTER 8 Anti-infective Agents
CHAPTER 9 Antimalarials
CHAPTER 10 Antibacterial Antibiotics
CHAPTER 11 Antiviral Agents
CHAPTER 12 Antineoplastic Agents
CHAPTER 13 Agents for Diagnostic Imaging
CHAPTER 14 Central Nervous System Depressants
CHAPTER 15 Central Nervous System Stimulants
CHAPTER 16 Adrenergic Agents
CHAPTER 17 Cholinergic Drugs and Related Agents
CHAPTER 18 Diuretics
CHAPTER 19 Cardiovascular Agents
CHAPTER 20 Local Anesthetic Agents
CHAPTER 21 Histamine and Antihistaminic Agents
CHAPTER 22 Analgesic Agents
CHAPTER 23 Steroids and Therapeutically Related Compounds
CHAPTER 24 Prostaglandins, Leukotrienes, and Other Eicosanoids
CHAPTER 25 Proteins, Enzymes, and Peptide Hormones
CHAPTER 26 Vitamins and Related Compounds
CHAPTER 27 An Introduction to the Medicinal Chemistry of Herbs
CHAPTER 28 Computational Chemistry and Computer-Assisted Drug Design
App Calculated Log P, Log D, and pK[subscript al
Index
