有机官能团Organic Functional Groups

分類: 图书,进口原版书,医学 Medicine ,
作者: Thomas L Lemke著
出 版 社: Oversea Publishing House
出版时间: 2003-9-1字数:版次:页数: 156印刷时间: 2003/09/01开本: 16开印次:纸张: 胶版纸I S B N : 9780781743815包装: 平装内容简介
Designed to be used as a self-paced review, this text outlines the functional groups common to organic chemistry, reviewing the general topics of nomenclature, physical and chemical properties, and metabolism. The text provides background material for the formal pharmacy courses in medicinal chemistry, easing the transition from general organic chemistry courses required of all pre-pharmacy students. The Fourth Edition will include a workbook on CD-ROM as well as an index on general drug metabolism. Students who use this text are able to complete difficult tasks such as: drawing a chemical structure or official chemical name; predicting solubility of chemicals in liquids; predicting and showing, with chemical structures, the metabolism of organic functional groups; predicting and showing instabilities, with chemical structures.
目录
Introduction
1 Water Solubility and Chemical Bonding
Van der Waals Attraction(Forces)
Dipole—Dipole Bonding(Hyd rogen Bond)
Ionic Attraction
Ion-Dipole Bonding
2 Alkanes(CnH2n+2)
3 Alkenes(CnH2 n)
Cycloalkanes:Alkene Isomers
4 Aromatic Hydrocarbons
5 Halogenated Hydrocarbons
6 Alcohols
7 Phenols
8 Ethers
9 Aldehydes and Ketones
10 Amines
Quaternary Ammonium Salts
11 Carboxylic Acids
12 Functional Derivatives of Carboxylic Acids
Esters
Amides
Carbonates,Carbamates,and Ureas
Amidines and Guanidines
13 Sulfonic Acids and Sulfonamides
Sulfonic Acids
Sulfonamides
14 Thioethers and Nitro Groups
Thioethers
Nitro Groups
15 Heterocycles
Th ree—Membered Ring Heterocydes
Four-Membered Ring Heterocycles
Five.Membered Ring Heterocycles
Five—Membered Ring Heterocycles With Two or More Heteroatoms
Six—Membered Ring Heterocycles
Six.Membered Ring Heterocycles With Two Heteroatoms
Saturated Six—Membered Heterocycles
Seven-—And Eight--Membered Ring Heterocycles
Bicyclic Heterocycles:Five—Membered Ring Plus Six.Membered Ring
Bicyclic Heterocycles:Six-Membered Ring Plus
Six—Membered Ring
Bicyclic Heterocycles:Six—Membered Ring Plus Seven-Membered Ring
Tricyclic Heterocycles
16 0Ugonucleotides and N ucleic Acids
17 Proteins
18 Predicting Water Solubility
Empi ric Method
Analytic Method
A Stereoisomerism--Asymmetric Motecules
B Acidity and Basicity
Definitions of Acids and Bases
Relative Strengths of Acids and Bases
Reaction of an Acid W;t}1 a Base in Water
Acidic and Basic Organic Function Groups
C Drug Metabolism
Oxygenase Enzymes
Hydrolase Enzymes
Conjugation Reactions
Index