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有机官能团Organic Functional Groups

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  分類: 图书,进口原版书,医学 Medicine ,

作者: Thomas L Lemke著

出 版 社: Oversea Publishing House

出版时间: 2003-9-1字数:版次:页数: 156印刷时间: 2003/09/01开本: 16开印次:纸张: 胶版纸I S B N : 9780781743815包装: 平装内容简介

Designed to be used as a self-paced review, this text outlines the functional groups common to organic chemistry, reviewing the general topics of nomenclature, physical and chemical properties, and metabolism. The text provides background material for the formal pharmacy courses in medicinal chemistry, easing the transition from general organic chemistry courses required of all pre-pharmacy students. The Fourth Edition will include a workbook on CD-ROM as well as an index on general drug metabolism. Students who use this text are able to complete difficult tasks such as: drawing a chemical structure or official chemical name; predicting solubility of chemicals in liquids; predicting and showing, with chemical structures, the metabolism of organic functional groups; predicting and showing instabilities, with chemical structures.

目录

Introduction

1 Water Solubility and Chemical Bonding

Van der Waals Attraction(Forces)

Dipole—Dipole Bonding(Hyd rogen Bond)

Ionic Attraction

Ion-Dipole Bonding

2 Alkanes(CnH2n+2)

3 Alkenes(CnH2 n)

Cycloalkanes:Alkene Isomers

4 Aromatic Hydrocarbons

5 Halogenated Hydrocarbons

6 Alcohols

7 Phenols

8 Ethers

9 Aldehydes and Ketones

10 Amines

Quaternary Ammonium Salts

11 Carboxylic Acids

12 Functional Derivatives of Carboxylic Acids

Esters

Amides

Carbonates,Carbamates,and Ureas

Amidines and Guanidines

13 Sulfonic Acids and Sulfonamides

Sulfonic Acids

Sulfonamides

14 Thioethers and Nitro Groups

Thioethers

Nitro Groups

15 Heterocycles

Th ree—Membered Ring Heterocydes

Four-Membered Ring Heterocycles

Five.Membered Ring Heterocycles

Five—Membered Ring Heterocycles With Two or More Heteroatoms

Six—Membered Ring Heterocycles

Six.Membered Ring Heterocycles With Two Heteroatoms

Saturated Six—Membered Heterocycles

Seven-—And Eight--Membered Ring Heterocycles

Bicyclic Heterocycles:Five—Membered Ring Plus Six.Membered Ring

Bicyclic Heterocycles:Six-Membered Ring Plus

Six—Membered Ring

Bicyclic Heterocycles:Six—Membered Ring Plus Seven-Membered Ring

Tricyclic Heterocycles

16 0Ugonucleotides and N ucleic Acids

17 Proteins

18 Predicting Water Solubility

Empi ric Method

Analytic Method

A Stereoisomerism--Asymmetric Motecules

B Acidity and Basicity

Definitions of Acids and Bases

Relative Strengths of Acids and Bases

Reaction of an Acid W;t}1 a Base in Water

Acidic and Basic Organic Function Groups

C Drug Metabolism

Oxygenase Enzymes

Hydrolase Enzymes

Conjugation Reactions

Index

 
 
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