医学文献的使用指南 Users＇Guides to the Medical Literature
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作者： Gordon H. Guyatt著
出 版 社： Oversea Publishing House
出版时间： 2001-7-1字数：版次： 1页数： 706印刷时间： 2001/07/01开本： 32开印次： 1纸张： 胶版纸I S B N ： 9781579471743包装： 平装内容简介
From the popular series in JAMA comes a state of the art book from the authors who coined the term evidence-based medicine. Edited by Gordon Guyatt, MD, and Drummond Rennie, MD, this highly innovative book enables physicians to quickly grasp efficient ways to use published literature in their clinical practice to improve their caregiving to patients. A fully searchable and hyperlinked CD, co-edited by Robert Hayward, MD, is included with each book.
With the most current evidence based medicine thinking, you can understand how to individualize evidence to each patient, obtain tips on how to find the information you need and how to make the optimal use of it in your practice, balance benefits and risks that precede medical management decisions, distinguish between strong and weak evidence, and understand detailed critical appraisal and summarization of evidence.
目录
Foreword
Preface
Contributors
How to Use This Book
Part 1 The Basics：Using the Medical Literature
1A Introduction：The Philosophy of Evidence-Based Medicine
1A1 Finding the Evidence
1B Therapy and Harm：An Introduction
1B1 Therapy
1B2 Harm
1C The Process of Diagnosis
1c1 Differential Diagnosis
1C2 Diagnostic Tests
1D Prognosis
1E Summarizing the Evidence
1F Moving From Evidence to Action
Part 2 Beyond the Basics：Using and Teaching the Principles of Evidence-Based Medicine
2A Expanded Philosophy of Evidence—Based Medicine
Parallel but Separate Goals--Evidence—Based
Practitioners and Evidence-Based Care
Criticisms of Evidence-Based Medicine
2B Therapy and Harm
Why Study Results Mislead--Bias and Random Error
Outcomes of Health Services
2B1 Therapy and Validity
Surprising Results of Randomized Controlled Trials
The Principle of Intention-to-Treat
N of l Randomized Controlled Trials
Computer Decision Support Systems
2B2 Therapy and Understanding the Results
Quality of Life
Hypothesis Testing
Confidence Intervals．．．．
Measures of Association
2B3 Therapy and Applying the Results
Applying Results to Individual Patients
Example Numbers Needed to Treat
Surrogate Outcomes
Drug Class Effects
Qualitative Research
2C Diagnosis
Clinical Manifestations of Disease
Measuring Agreement Beyond Chance
Clinical Prediction Rules
Examples of Likelihood Ratios
2D Prognosis
Regression and Correlation
2E Summarizing the Evidence
Publication Bias
Fixed-Effects and Random—Effects Models
Evaluating Differences in Study Results
When to Believe a Subgroup Analysis
2F Moving From Evidence to Action
Incorporating Patient Values
Recommendations About Screening
Grading Recommendations-A Qualitative Approach
Grading Recommendations-A Quantitative Approach
Economic Analysis
Clinical Utilization Review
Appendix
Glossary
CD—ROM Installation Instructions
Index
