Biology and Pathology of Trophoblast胚胎滋养层生物学和病理学
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分類: 图书,进口原版书,医学 Medicine ,
作者: Ashley Moffett,Charlie Loke,Anne McLaren著
出 版 社:
出版时间: 2006-5-1字数:版次: 1页数: 272印刷时间: 2006/05/01开本: 16开印次: 1纸张: 胶版纸I S B N : 9780521851657包装: 精装内容简介
“Readers who want a more scientific treatise on the wonders of the placenta should peruse Biology and Pathology of Trophoblast。provide succinct yet comprehensive introductions to a number of important immunologic concepts pertinent to the process of placentation and the maintenance of pregnancy。 Many interesting facts about placental immunology are shared。”
Drucilla J.Robers,M.D., Massachusetts General Hospital, New England Journal of Medicine。
This is the first dedicated, in-depth account of trophoblast: the tissue derived from the fertilized egg that nourishes and protects the developing fetus。 The cells of the trophoblast have many unique qualities, and exhibit great variability across different species。 It has a fascinating role in the development of the placenta and as a regulator during early growth of the embryo。 These aspects are all fully covered as well as studies on why it is not rejected by the mother as ‘foreign’ tissue。 This volume provides an up-to-date summary of the state of current knowledge and offers some glimpses as to future development on the scientific and clinical front。
目录
List of contributors
List of participants
Preface
Y.W.(Charlie) Loke
Chair’s introduction
1Trophoblast cell fate specification
2Stem cells: pluripotency and extraembryonic differentiationin the mouse
3Epigenetic regulation of trophoblast development
4Regulation of X-chromosome inactivation in relation to lineageallocation in early mouse embryogenesis
General discussion Ⅰ
5Gestational trophoblastic disease
6Trophoblast and the first trimester environment
7Implantation is a sticky situation
8Trophoblast regulation of maternal endocrine functionand behaviour
General discussion Ⅱ
9Molecular signalling in embryo-uterine interactionsduring implantation
10Trophoblast and pre-eclampsia
11Trophoblast and uterine mucosal leukocytes
12Immunology of trophoblast: a reappraisal
Final general discussion
Index