男， 1954年生， 四川大学工学硕士，理学博士。1997年12月至1999年5在月香港理工大学任博士后研究员. 1999年5月至2000年5月台湾中兴大学任博士后研究员. 2000年8月至2004年4在香港理工大学应用生物及化学科技系担任研究员, 2004年4月至2005年4月在日本岗山理科大学应用化学系研究员. 2005年4月到中山大学药学院药物化学研究所工作.教授,博士生导师,在国际国内重要刊物发表论文60余篇, Sci收录40余篇.
研究方向:手性药物合成及相关基础和应用基础研究
曾讲授课程: 有机化学, 中草药成份化学.
拟讲授课程: 手性药物合成
承担科研项目: 国家自然科学基金1 项, 负责, 22.00万, 2005-2007; 广东省基金1项, 负责, 6.00万, 2005-2007; 中山大学引进人才科研起动基金, 50.00万, 2005-2007.
Email: xsli219@yahoo.com
代表性论著:
1.Xian Jia, Xingshu Li*, Wing Sze Lam, Stanton H. L. Kok, Lijin Xu, Gui Lu, Chi-Hung Yeung and Albert S. C. Chan*, The synthesis of new chiral phosphine–phosphinites, phosphine–phosphoramidite, and phosphine–phosphite ligands and their applications in asymmetric hydrogenation. Tetrahedron: Asymmetry, 15, 2004, 2273.
2.Xian Jia, Xinngshu Li, Lijin Xu, Yueming Li, Qian Shi, Terry T.-L. Au-Yeung, C. W. Yip, Xingsheng Yao and Albert S. C. Chan*, Titanium-catalyzed Tandem sulfoxidation-kinetic Resolution Process: a convenient Method for Higher Enantioselectivities and Yield of Chiral Sulfoxide, Advvanced Synthesis & Catalysis, 2004, 346, 723-726.
3.Xian Jia, Xinshu Li*, Lijin Xu, Qian, Shi, Xinsheng Yao and Albert S.C. Chan*. A highly efficient rhodium/monodentate phosphoramidite catalyst and its application in the enantioselective hydrogenation of enamides and ?-dehydroamino acid derivatives. Journal of Organic Chemistry. 2003, 68(11), 4539-4541.
4.Gui Lu, Xingshu Li, Xian Jia, Wing Lai Chan, Albert S. C. Chan, Enantioselective alkynylation of aromatic ketones catalyzed by chiral camphorsulfonamide ligands. Angewandte Chemie, International Edition 2003, 42(41), 5057-5058
5.Liming Su, Xingshu Li*, Wing Lai Chan, Xian Jia, Albert S. C. Chan*, Copper-catalyzed enantioselective conjugate addition of triethylaluminum to 2-cyclopentenone. Tetrahedron: Asymmetry. 2003, 14(13), 1865-1869.
6.Xinshu Li, Xian Jia, Gui Lu, Terry T.-L. Au-yeung, Kim-Hung Lam, Thomas W. H. Lo and Albert S.C. Chan. Highly enantioselective hydrogenation of enamides catalyzed by rhodium-monodentate phosphoramidites derived from H8-BINOL. Tetrahedron Asymmetry. 2003, 14(18).2687-2691
7.Lijin Xu, Qian Shi, Xingshu Li*, Xian Jia, Xin Huang, Ruihu Wang, Zhongyuan Zhou, Zhenyang Lin, Albert S. C. Chan*. Formation of a palladium (II) complex of 2-(2-pyridinylmethyleneamino)-2'-hydroxy-1,1'-binaphthyl with novel Cσ-coordination and its theoretical investigation. Chemical Communications (Cambridge, United Kingdom) 2003, 14, 1666-1667
8.Qian Shi, Lijin Xu, Xingshu Li*, Xian Jia, Ruihu Wang, Terry T.-L. Au-Yeung, Albert S.C. Chan, Tamio Hayashi, Rong Cao and Maochun Hong. Bipyridyl-based diphosphine as an efficient ligand in the rhodium-catalyzed asymmetric conjugate addition of arylboronic acids to á,a-unsaturated ketones. Tetrahedron Letter. 2003, 44, 6505-6508.
